Which places in the Ústí nad Labem Region need booking?

You don't need to book ahead for any of them.

What's seasonal in the Ústí nad Labem Region?

Seasonal: Pravčická Gate (Apr–Nov) and Ore Mountains (Jun–Oct). The others aren't seasonal, but check opening hours before you go.

By car, Pinsko's places here are 40 min–2 h 5 min from Prague and 2 h 45 min–4 h 5 min from Brno, without traffic.

Pinsko lists 14 places in the Ústí nad Labem Region: 4 beer stops, 3 wine stops, 3 nature spots, 2 historic sites, 1 spa town and 1 mushroom area.

Highlights include Temple of Hops and Beer, Žatec; Velké Žernoseky and Pravčická Gate.

Which places in the Ústí nad Labem Region need booking?: You don't need to book ahead for any of them.
What's seasonal in the Ústí nad Labem Region?: Seasonal: Pravčická Gate (Apr–Nov) and Ore Mountains (Jun–Oct). The others aren't seasonal, but check opening hours before you go.
How far is the Ústí nad Labem Region from Prague and Brno?: By car, Pinsko's places here are 40 min–2 h 5 min from Prague and 2 h 45 min–4 h 5 min from Brno, without traffic.

TepliceWalk-in
One of the oldest spas in Europe, where hot springs have been used since the Middle Ages and which later drew European nobility.

Ore MountainsWalk-in
Birch and spruce on the ridge above the spa towns — birch boletes and milk caps, late July into October.